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Objective To observe the effect of the trinity comprehensive therapy for adolescent pseudo-myopia.Methods According to the digital table,149 patients(298 eyes) were divided into the observation group75 patients(150 eyes) and the control group74 patients(148 eyes).The observation group were given with the trinity comprehensive therapy:herbal acupoint massage,auricular-plaster therapy and to wear the crystal apparatus.The control group were given with 0.5％ tropicamide eye drops.Based on the naked distant vision,this paper will observe their respective curative effect,and then make the statistical analysis afterwards.Results The effective rate in the observation group was(95.14％),which was significantly higher than (78.26％)of the control group (Z =-12.563,P ＜ 0.05).Meanwhile,the effect of the treatment on the naked visual acuity in pseudo-myopia who were with (0.8 ± 0.1) was significantly higher than that of the naked visual acuity of the patients with low vision.And after a half-a-year treatment,the vision loss rate in the observation group was significantly lower than that in the control group(P ＜0.05).Conclusion The curative effect of the trinity comprehensive therapy for adolescent pseudo-myopia is definite,and can be maintained for a long time,which has a certain value to prevent the occurrence and development of juvenile myopia.
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Objective To explore the level of free fatty acid (FFA)in ischemic stroke (IS) patients and its correlation with insulin resistance (IR).Methods This study was case-control study.Patients who were diagnosed with IS were followed up from June,2011 to September,2012 in Tianjin Third Central Hospital.The 180 IS patients were divided into large infarct(57),middle infarct(63)and small infarct (60) according to the area of infarct.At the same time,60 healthy persons were selected as control group.The plasma FFA,fasting insulin (FINS),fasting blood glucose (FBG),homeostasis model assessment (HOMA)-IR,triacylglycerol (TG),total cholesterol (TC),high density lipoprotein cholesterol-C (HDL),low density lipoprotein cholesterol-C(LDL),lipoprotein A1 (APOA1) and lipoprotein B (APOB) in 180 IS patients were measured and compared with that of control group.The correlation between FFA and IR was analyzed by using pearson linear correlation.The relationship between FFA and HOMA-IR was analyzed by using multiple stepwise multivariate analysis.The t test and analysis of variance were used for statistical analysis.Results Compared to normal control,the level of FFA,FINS,FBG,FIB,TG,TC,LDL,APOB and HOMA-IR in IS patients were higher,the difference was statistically.The level of HDL,APOA1 in IS patients were lower than that of normal control.The level of FFA,FINS,HOMA-IR,FBG,TG,TC,HDL,LDL,APOA1 and APOB in IS patients related to the area of infarct.The level of FFA,FINS,HOMA-IR,FBG,TG,TC,LDL,APOB in large infarct were higher than those in middle infarct and small infarct.The level of HDL,APOA1 in large infarct were lower than those in middle infarct and small infarct,the difference were statistically.In IS patients,FFA had positive correlation to FINS,FBG and HOMA-IR (r =0.870,0.497,0.792,P ＜ 0.001),but had no correlation to age (r =0.008,P ＞ 0.05).In IS patients,HOMA-IR was dependent variable,but FFA,FINS,FBG,TG,TC,HDL,APOA1 and APOB were independent variable.FFA was independent risk factor to HOMA-IR,besides FINS,FBG,TC,LDL and APOB.Conclusion FFA elevates in IS patients,FFA has correlation to IR and it is a dependent risk factor to IS patients.
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Epilepsy is a brain dysfunction syndrome resulted from many causes,which is closely related to age,especially occuring in the immature brain.Long-term,repeated seizures can lead to immature brain tissue damage,and increase susceptibility of immature brain to epileptic brain damage.Not only does substantia nigra network have the effect of delicate anticonvulsion,but it is also vulnerable to epilepticseizures.Protecting the immature brain substantia nigra pars can prevent or reduce the risk of seizures,epilepsy has an important role in brain injury recovery.Giving children the brain protective drugs aimed directly at substantia nigra pars is a viable and effective method to treat epileptic brain injury.
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Objective To analyze the new breeding of eggplant "HANGQIE-5"(HQ-5) generated by space mutagenesis with RAPD,identify the differential RAPD bands,and try to provide molecular proofs for space mutation breeding.Methods Dry seeds of two eggplants "Tianshuichangqie(TSCQ)" and Longguoyuanqie(LGYQ) were carried by "shenzhou-4" and "shenzhou-3"spaceship.Two mutant lines "TSCQ-MUT-4" and "LGYQ-MUT-4" were selected after four generations of self-cross of TSCQ and LGYQ.A new variety of "HQ-5" was selected by crossing the two lines of "TSCQ-MUT-4" and "LGYQ-MUT-4",which were male and female,respectively.The RAPD reaction system was optimized with orthogonal design and further RAPD analysis was applied.Results The RAPD reaction system was determined as follows: DNA: 40 ng,dNTPs: 7.5 nmol,primer: 10 ng,and rTaq polymerase: 1.25 U.The RAPD results displayed that TSCQ-MUT-4 produced four differential bands compared with its wild type,while LGYQ-MUT-4 produced one,through space flight.Six differential fragments were amplified between HQ-5 and the paternal/maternal.HQ-5 not only shared the common fragments with its parents,but also held some particular ones,which were stably inherited.Conclusion The results indicate that space mutagenesis could cause mutations in DNA of plants,and is helpful to generate a new breeding.